Probably for decades women and medical profession were perplexed with the issue of fibroids developed in uterus and bothering females.The cause of fibroids are not clearly known. Problems such as how to reduce excessive bleeding in women who have fibroids,impact of it on fertility and IVF treatment,do fibroid develop into sarcoma,are the present surgery even if a laparoscopic really safe,how to reduce recurrence after surgical treatment of fibroids,impact on pregnancy are unsolved.
Indian Gynaecological Endoscopisthas treated highest numbers of fibroids in the world in terms of size,number,type of fibroids,exceptional methods of laparoscopic suturing.The total Women's Health Care technique of morcellating the fibroids or large uterus with fibroids in bag avoiding spillage in more than 210 cases is the largest in the world. Yet the best and genius falls short of complete solution.
Nisha,a 23 year old unmarried female has 8 cms fibroid with excessive bleeding not responding to regular medicine.She is not keen for open or laparoscopic surgery.Her quality of life is affected by low hemoglobin.
Asha Desai, a 33 year old female married for six years has three fibroids of 5-6 cms removed as is keen for conception.Neither the gynaecologist nor her family has an answer to the recurrence of fibroids.
Ananya Jain,a 36 year old lady is planning for IVF due to sperm count issues but has two fibroids of 6-7 cms.She and the IVF expert don't know the best method.
Mona Singh,a 42 year old woman who had two caesarean deliveries,has fibroids and excessive bleeding since the past two to three years and is not keen for removal of uterus or surgery.Aruna Khatri,a 47 year old lady has eight cms fibroid with post-menopausal bleeding,hypertension,diabetes and obesity wants concerte treatment without surgery as her uterine cavity is thin and normal.
Al these group of females used to have various treatment of a depo injection medicated IUCD,suggestion of surgery or MRI guided focused ultrasound treatment with no assurance.
Now they can have a sigh of relief as the major cause of fibroids was progesterone and progesterone receptor.The new drug Ulipristal Acetate a selective progesterone receptor modulator can be given to all these female in the doze of 5-10 mg for a period of three months and if necessary repeated after two months.
The complaint of bleeding, pain etc were reduced in 70-90 per cent of the cases and in eight out ten per cent surgeries were avoided. Their quality of life and hemoglobin improved.Fortunately there are no major side effects.The drug brings about apoptosis that is myoma cell death and also organises the surrounding matrix of fibroid keeping uterus unaffected.The recurrence rate dropped and if IVF or surgery was needed than that could be easily performed after three months of Ulipristal Acetate,with a gap of further two months they could plan their pregnancy or IVF as necessary.
The Total Women's Health Care Hospital, Ghatkopar, Mumbai, India has the largest experience of fibroid removal,research on fibroid and infertility outcome,has been using Ulipristal Acetate in innumerable number of patients of fibroids.The number of surgeries for fibroids and recurrence has dropped to more than 50-60 per cent.
Dr.Prakash Trivedi,a pioneer in Laparoscopic surgery,IVF and a clinician uses Ulipristal Acetate precisely and has educated nearly 3000 Gynaecologist of India to improve women's health care.
Dr.Trivedi has profound research in fibroids,female urinary leak,removal of large uterus with fibroids and is a sorted after teacher.He feel finally something concrete in the form of tablets at reasonable cost is now in the hands of various gynecologist who can treat women with problems of fibroids and also avoid surgery.On going research will prove more benefits in the outcome for better women's health.
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